(R)-Nepicastat HCl

CAS No. 195881-94-8

(R)-Nepicastat HCl ( —— )

Catalog No. M17411 CAS No. 195881-94-8

(R)-Nepicastat HCl, the R-enantiomer of Nepicastat HCl, is a potent and selective inhibitor with IC50 of 25.1 nM and 18.3 nM for bovine and human dopamine-β-hydroxylase, with negligible affinity for twelve other enzymes and thirteen neurotransmitter receptors.

Purity : 98%

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 122 Get Quote
10MG 206 Get Quote
25MG 389 Get Quote
50MG 527 Get Quote
100MG 770 Get Quote
200MG Get Quote Get Quote
500MG Get Quote Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    (R)-Nepicastat HCl
  • Note
    Research use only, not for human use.
  • Brief Description
    (R)-Nepicastat HCl, the R-enantiomer of Nepicastat HCl, is a potent and selective inhibitor with IC50 of 25.1 nM and 18.3 nM for bovine and human dopamine-β-hydroxylase, with negligible affinity for twelve other enzymes and thirteen neurotransmitter receptors.
  • Description
    (R)-Nepicastat HCl, the R-enantiomer of Nepicastat HCl, is a potent and selective inhibitor with IC50 of 25.1 nM and 18.3 nM for bovine and human dopamine-β-hydroxylase, with negligible affinity for twelve other enzymes and thirteen neurotransmitter receptors.
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Dopamine β-hydroxylase; Dopamine β-hydroxylase
  • Research Area
    Cardiovascular Disease
  • Indication
    ——

Chemical Information

  • CAS Number
    195881-94-8
  • Formula Weight
    331.81
  • Molecular Formula
    C14H15F2N3S·HCl
  • Purity
    98%
  • Solubility
    ——
  • SMILES
    Cl.NCC1=CNC(=S)N1[C@@H]1CCC2=C(F)C=C(F)C=C2C1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Stanley WC, et al. Br J Pharmacol. 1997, 121(8), 1803-1809.
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